References
[1] E. Mutuyemungu, M. Singh, S. Liu, and D. J. Rose, “Intestinal gas production by the gut microbiota: A review,” Journal of Functional Foods, vol. 100, p. 105367, Jan. 2023, doi: 10.1016/j.jff.2022.105367.
[2] S. Crucillà, F. Caldart, M. Michelon, G. Marasco, and A. Costantino, “Functional Abdominal Bloating and Gut Microbiota: An Update,” Microorganisms, vol. 12, no. 8, p. 1669, Aug. 2024, doi: 10.3390/microorganisms12081669.
[3] T. Ohkusa, S. Koido, Y. Nishikawa, and N. Sato, “Gut Microbiota and Chronic Constipation: A Review and Update,” Front Med (Lausanne), vol. 6, p. 19, Feb. 2019, doi: 10.3389/fmed.2019.00019.
[4] M. A. Iancu, M. Profir, O. A. Roşu, R. F. Ionescu, S. M. Cretoiu, and B. S. Gaspar, “Revisiting the Intestinal Microbiome and Its Role in Diarrhea and Constipation,” Microorganisms, vol. 11, no. 9, p. 2177, Aug. 2023, doi: 10.3390/microorganisms11092177.
[5] P. A. Nieto et al., “Improving immune-related health outcomes post-cesarean birth with a gut microbiome-based program: A randomized controlled trial,” Pediatr Allergy Immunol, vol. 36, no. 9, p. e70182, Sep. 2025, doi: 10.1111/pai.70182.
[6] S. R. Ellis et al., “The Skin and Gut Microbiome and Its Role in Common Dermatologic Conditions,” Microorganisms, vol. 7, no. 11, p. 550, Nov. 2019, doi: 10.3390/microorganisms7110550.
[7] S. Widhiati, D. Purnomosari, T. Wibawa, and H. Soebono, “The role of gut microbiome in inflammatory skin disorders: A systematic review,” Dermatol Reports, vol. 14, no. 1, p. 9188, Dec. 2021, doi: 10.4081/dr.2022.9188.
[8] I. Salem, A. Ramser, N. Isham, and M. A. Ghannoum, “The Gut Microbiome as a Major Regulator of the Gut-Skin Axis,” Front Microbiol, vol. 9, p. 1459, 2018, doi: 10.3389/fmicb.2018.01459.
[9] Y. B. Lee, E. J. Byun, and H. S. Kim, “Potential Role of the Microbiome in Acne: A Comprehensive Review,” J Clin Med, vol. 8, no. 7, p. 987, Jul. 2019, doi: 10.3390/jcm8070987.
[10] H. J. Seong, Y. Baek, S. Lee, and H.-J. Jin, “Gut microbiome and metabolic pathways linked to sleep quality,” Front. Microbiol., vol. 15, Jul. 2024, doi: 10.3389/fmicb.2024.1418773.
[11] M. Heddes et al., “The intestinal clock drives the microbiome to maintain gastrointestinal homeostasis,” Nat Commun, vol. 13, no. 1, p. 6068, Oct. 2022, doi: 10.1038/s41467-022-33609-x.
[12] K. D. Corbin et al., “Host-diet-gut microbiome interactions influence human energy balance: a randomized clinical trial,” Nat Commun, vol. 14, no. 1, p. 3161, May 2023, doi: 10.1038/s41467-023-38778-x.
[13] J.-H. Wang, Y. Choi, J.-S. Lee, S.-J. Hwang, J. Gu, and C.-G. Son, “Clinical evidence of the link between gut microbiome and myalgic encephalomyelitis/chronic fatigue syndrome: a retrospective review,” Eur J Med Res, vol. 29, p. 148, Mar. 2024, doi: 10.1186/s40001-024-01747-1.
[14] F. Valitutti et al., “Intestinal permeability, food antigens and the microbiome: a multifaceted perspective,” Front. Allergy, vol. 5, Jan. 2025, doi: 10.3389/falgy.2024.1505834.
[15] F. Di Vincenzo, A. Del Gaudio, V. Petito, L. R. Lopetuso, and F. Scaldaferri, “Gut microbiota, intestinal permeability, and systemic inflammation: a narrative review,” Intern Emerg Med, vol. 19, no. 2, pp. 275–293, Mar. 2024, doi: 10.1007/s11739-023-03374-w.
[16] P. Gazerani, L. Papetti, T. Dalkara, C. L. Cook, C. Webster, and J. Bai, “The Brain, the Eating Plate, and the Gut Microbiome: Partners in Migraine Pathogenesis,” Nutrients, vol. 16, no. 14, p. 2222, Jul. 2024, doi: 10.3390/nu16142222.
[17] R. Guo, L.-H. Chen, C. Xing, and T. Liu, “Pain regulation by gut microbiota: molecular mechanisms and therapeutic potential,” Br J Anaesth, vol. 123, no. 5, pp. 637–654, Nov. 2019, doi: 10.1016/j.bja.2019.07.026.
[18] B. Bonaz, T. Bazin, and S. Pellissier, “The Vagus Nerve at the Interface of the Microbiota-Gut-Brain Axis,” Front. Neurosci., vol. 12, Feb. 2018, doi: 10.3389/fnins.2018.00049.
[19] N. Akram et al., “Exploring the serotonin-probiotics-gut health axis: A review of current evidence and potential mechanisms,” Food Sci Nutr, vol. 12, no. 2, pp. 694–706, Feb. 2024, doi: 10.1002/fsn3.3826.
[20] E. A. Mayer, K. Nance, and S. Chen, “The Gut-Brain Axis,” Annu Rev Med, vol. 73, pp. 439–453, Jan. 2022, doi: 10.1146/annurev-med-042320-014032.
[21] J. A. Foster, L. Rinaman, and J. F. Cryan, “Stress & the gut-brain axis: Regulation by the microbiome,” Neurobiol Stress, vol. 7, pp. 124–136, Dec. 2017, doi: 10.1016/j.ynstr.2017.03.001.
[22] A. Rutsch, J. B. Kantsjö, and F. Ronchi, “The Gut-Brain Axis: How Microbiota and Host Inflammasome Influence Brain Physiology and Pathology,” Front Immunol, vol. 11, p. 604179, 2020, doi: 10.3389/fimmu.2020.604179.
[23] J. Noor, A. Chaudhry, S. Batool, R. Noor, and G. Fatima, “Exploring the Impact of the Gut Microbiome on Obesity and Weight Loss: A Review Article,” Cureus, vol. 15, no. 6, p. e40948, doi: 10.7759/cureus.40948.
[24] D. Chanda and D. De, “Meta-analysis reveals obesity associated gut microbial alteration patterns and reproducible contributors of functional shift,” Gut Microbes, vol. 16, no. 1, p. 2304900, 2024, doi: 10.1080/19490976.2024.2304900.
[25] J. Geng, Q. Ni, W. Sun, L. Li, and X. Feng, “The links between gut microbiota and obesity and obesity related diseases,” Biomed Pharmacother, vol. 147, p. 112678, Mar. 2022, doi: 10.1016/j.biopha.2022.112678.
[26] S. P. Wiertsema, J. van Bergenhenegouwen, J. Garssen, and L. M. J. Knippels, “The Interplay between the Gut Microbiome and the Immune System in the Context of Infectious Diseases throughout Life and the Role of Nutrition in Optimizing Treatment Strategies,” Nutrients, vol. 13, no. 3, p. 886, Mar. 2021, doi: 10.3390/nu13030886.
[27] J. Y. Yoo, M. Groer, S. V. O. Dutra, A. Sarkar, and D. I. McSkimming, “Gut Microbiota and Immune System Interactions,” Microorganisms, vol. 8, no. 10, p. 1587, Oct. 2020, doi: 10.3390/microorganisms8101587.
[28] Y. Belkaid and T. W. Hand, “Role of the microbiota in immunity and inflammation,” Cell, vol. 157, no. 1, pp. 121–141, Mar. 2014, doi: 10.1016/j.cell.2014.03.011.
[29] D. Rondinella et al., “The Detrimental Impact of Ultra-Processed Foods on the Human Gut Microbiome and Gut Barrier,” Nutrients, vol. 17, no. 5, p. 859, Jan. 2025, doi: 10.3390/nu17050859.
[30] G. Cusumano, G. A. Flores, R. Venanzoni, and P. Angelini, “The Impact of Antibiotic Therapy on Intestinal Microbiota: Dysbiosis, Antibiotic Resistance, and Restoration Strategies,” Antibiotics (Basel), vol. 14, no. 4, p. 371, Apr. 2025, doi: 10.3390/antibiotics14040371.
[31] A. Safarchi, G. Al-Qadami, C. D. Tran, and M. Conlon, “Understanding dysbiosis and resilience in the human gut microbiome: biomarkers, interventions, and challenges,” Front. Microbiol., vol. 16, Mar. 2025, doi: 10.3389/fmicb.2025.1559521.
[32] P. Ferretti, “The gut remembers: the long-lasting effect of medication use on the gut microbiome,” mSystems, vol. 10, no. 10, p. e0107625, Oct. 2025, doi: 10.1128/msystems.01076-25.
[33] A. A. Madison and M. T. Bailey, “Stressed to the Core: Inflammation and Intestinal Permeability Link Stress-Related Gut Microbiota Shifts to Mental Health Outcomes,” Biol Psychiatry, vol. 95, no. 4, pp. 339–347, Feb. 2024, doi: 10.1016/j.biopsych.2023.10.014.
[34] G. Li et al., “Sleep Deprivation Impairs Intestinal Mucosal Barrier by Activating Endoplasmic Reticulum Stress in Goblet Cells,” Am J Pathol, vol. 194, no. 1, pp. 85–100, Jan. 2024, doi: 10.1016/j.ajpath.2023.10.004.
[35] V. Monda et al., “Exercise Modifies the Gut Microbiota with Positive Health Effects,” Oxid Med Cell Longev, vol. 2017, p. 3831972, 2017, doi: 10.1155/2017/3831972.
[36] M. U. Sohail, H. M. Yassine, A. Sohail, and A. A. Al Thani, “Impact of Physical Exercise on Gut Microbiome, Inflammation, and the Pathobiology of Metabolic Disorders,” Rev Diabet Stud, vol. 15, pp. 35–48, 2019, doi: 10.1900/RDS.2019.15.35.
[37] C.-H. Kuo, L.-L. Wu, H.-P. Chen, J. Yu, and C.-Y. Wu, “Direct effects of alcohol on gut-epithelial barrier: Unraveling the disruption of physical and chemical barrier of the gut-epithelial barrier that compromises the host-microbiota interface upon alcohol exposure,” J Gastroenterol Hepatol, vol. 39, no. 7, pp. 1247–1255, Jul. 2024, doi: 10.1111/jgh.16539.
[38] G. Chen et al., “Gut microbiota dysbiosis: The potential mechanisms by which alcohol disrupts gut and brain functions,” Front. Microbiol., vol. 13, Jul. 2022, doi: 10.3389/fmicb.2022.916765.
[39] M. F. Butt et al., “Irritable Bowel Syndrome in Inflammatory Bowel Disease: An Evidence-Based Practical Review,” Journal of Clinical Medicine, vol. 15, no. 1, p. 116, Jan. 2026, doi: 10.3390/jcm15010116.
[40] K. Hodgkinson et al., “Butyrate’s role in human health and the current progress towards its clinical application to treat gastrointestinal disease,” Clin Nutr, vol. 42, no. 2, pp. 61–75, Feb. 2023, doi: 10.1016/j.clnu.2022.10.024.
[41] F. Di Lorenzo, C. De Castro, A. Silipo, and A. Molinaro, “Lipopolysaccharide structures of Gram-negative populations in the gut microbiota and effects on host interactions,” FEMS Microbiol Rev, vol. 43, no. 3, pp. 257–272, May 2019, doi: 10.1093/femsre/fuz002.
[42] S. Mohammad and C. Thiemermann, “Role of Metabolic Endotoxemia in Systemic Inflammation and Potential Interventions,” Front. Immunol., vol. 11, Jan. 2021, doi: 10.3389/fimmu.2020.594150.
[43] J. D. Braga, M. Thongngam, and T. Kumrungsee, “Gamma-aminobutyric acid as a potential postbiotic mediator in the gut-brain axis,” NPJ Sci Food, vol. 8, no. 1, p. 16, Apr. 2024, doi: 10.1038/s41538-024-00253-2.
[44] D. Belelli, J. J. Lambert, M. L. Y. Wan, A. R. Monteiro, D. J. Nutt, and J. D. Swinny, “From bugs to brain: unravelling the GABA signalling networks in the brain–gut–microbiome axis,” Brain, vol. 148, no. 5, pp. 1479–1506, May 2025, doi: 10.1093/brain/awae413.